Simultaneous analysis of T helper subsets (Th1, Th2, Th9, Th17, Th22, Tfh, Tr1 and Tregs) markers expression in periapical lesions reveals multiple cytokine clusters accountable for lesions activity and inactivity status

Simultaneous analysis of T helper subsets (Th1, Th2, Th9, Th17, Th22, Tfh, Tr1 and Tregs) markers expression in periapical lesions reveals multiple cytokine clusters accountable for lesions activity and inactivity status

Previous studies demonstrate that the balance between pro- and anti-inflammatory mediators determines the stable or progressive nature of periapical granulomas by modulating the balance of the osteoclastogenic factor RANKL and its antagonist OPG. However, the cytokine networks operating in the devel...

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Bibliographic Details
Main Authors: Ana Claudia ARAUJO-PIRES, Carolina Favaro FRANCISCONI, Claudia Cristina BIGUETTI, Franco CAVALLA, Andreza Maria Fabio ARANHA, Ariadne LETRA, Ana Paula Favaro TROMBONE, Marcelo FAVERI, Renato Menezes SILVA, Gustavo Pompermaier GARLET
Format: Article
Language:English
Published: University of São Paulo 2014-07-01
Series:Journal of Applied Oral Science
Subjects:
Apical granuloma
Cytokine networks
Immunoregulation
Immunology
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572014000400336&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572014000400336&lng=en&tlng=en

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