ACTH antagonists

ACTH antagonists

ACTH acts via a highly selective receptor that is a member of the melanocortin receptor subfamily of type 1 G protein-coupled receptors. The ACTH receptor, also known as the melanocortin 2 receptor (MC2R) is unusual in that it is absolutely dependent on a small accessory protein, melanocortin recept...

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Bibliographic Details
Main Authors: Adrian John Clark, Li Chan, Mashal Hussain, Rachel Forfar, Jeff Jerman, Ed McIver, Debra Taylor
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Endocrinology
Subjects:
G protein-coupled receptor
High throughput screening
adrenocorticotropin hormone
congenital adrenal hyperplasia
Cushing's syndrome
Receptor modelling
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2016.00101/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2016.00101/full

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