Crosstalk between autophagy and epithelial-mesenchymal transition and its application in cancer therapy

Crosstalk between autophagy and epithelial-mesenchymal transition and its application in cancer therapy

Abstract Autophagy is a highly conserved catabolic process that mediates degradation of pernicious or dysfunctional cellular components, such as invasive pathogens, senescent proteins, and organelles. It can promote or suppress tumor development, so it is a “double-edged sword” in tumors that depend...

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Bibliographic Details
Main Authors: Hong-Tao Chen, Hao Liu, Min-Jie Mao, Yuan Tan, Xiang-Qiong Mo, Xiao-Jun Meng, Meng-Ting Cao, Chu-Yu Zhong, Yan Liu, Hong Shan, Guan-Min Jiang
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Molecular Cancer
Subjects:
Autophagy
Epithelial-mesenchymal transition
Cancer metastasis
Anticancer therapy
Online Access:http://link.springer.com/article/10.1186/s12943-019-1030-2

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http://link.springer.com/article/10.1186/s12943-019-1030-2

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