Data-adaptive image-denoising for detecting and quantifying nanoparticle entry in mucosal tissues through intravital 2-photon microscopy

Data-adaptive image-denoising for detecting and quantifying nanoparticle entry in mucosal tissues through intravital 2-photon microscopy

Intravital 2-photon microscopy of mucosal membranes across which nanoparticles enter the organism typically generates noisy images. Because the noise results from the random statistics of only very few photons detected per pixel, it cannot be avoided by technical means. Fluorescent nanoparticles con...

Full description

Bibliographic Details
Main Authors: Torsten Bölke, Lisa Krapf, Regina Orzekowsky-Schroeder, Tobias Vossmeyer, Jelena Dimitrijevic, Horst Weller, Anna Schüth, Antje Klinger, Gereon Hüttmann, Andreas Gebert
Format: Article
Language:English
Published: Beilstein-Institut 2014-11-01
Series:Beilstein Journal of Nanotechnology
Subjects:
2-photon microscopy (2PM)
denoising
in vivo imaging
nanoparticles
signal to noise ratio (SNR)
quantum dots
Online Access:https://doi.org/10.3762/bjnano.5.210

Internet

https://doi.org/10.3762/bjnano.5.210

Similar Items