Distinct genomic subclasses of high-grade/progressive meningiomas: NF2-associated, NF2-exclusive, and NF2-agnostic

Distinct genomic subclasses of high-grade/progressive meningiomas: NF2-associated, NF2-exclusive, and NF2-agnostic

Abstract Background Genomic studies of high-grade/progressive meningiomas have reported a heterogeneous mutation spectrum, identifying few recurrently mutated genes. Most studies have been underpowered to detect genomic subclasses of aggressive meningiomas due to relatively small number of available...

Full description

Bibliographic Details
Main Authors: Erik A. Williams, Sandro Santagata, Hiroaki Wakimoto, Ganesh M. Shankar, Fred G. Barker, Radwa Sharaf, Abhinav Reddy, Phoebe Spear, Brian M. Alexander, Jeffrey S. Ross, Priscilla K. Brastianos, Daniel P. Cahill, Shakti H. Ramkissoon, Tareq A. Juratli
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Acta Neuropathologica Communications
Subjects:
Meningioma
1p loss
Progressive
NF2
TERT
PBRM1
Online Access:http://link.springer.com/article/10.1186/s40478-020-01040-2

Internet

http://link.springer.com/article/10.1186/s40478-020-01040-2

Similar Items