Characterization of Ixophilin, a thrombin inhibitor from the gut of Ixodes scapularis.

Ixodes scapularis, the black-legged tick, vectors several human pathogens including Borrelia burgdorferi, the agent of Lyme disease in North America. Pathogen transmission to the vertebrate host occurs when infected ticks feed on the mammalian host to obtain a blood meal. Efforts to understand how t...

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Bibliographic Details
Main Authors: Sukanya Narasimhan, Oriana Perez, Sara Mootien, Kathleen DePonte, Raymond A Koski, Erol Fikrig, Michel Ledizet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3706618?pdf=render