Mitochondrial mutations in subjects with psychiatric disorders.

A considerable body of evidence supports the role of mitochondrial dysfunction in psychiatric disorders and mitochondrial DNA (mtDNA) mutations are known to alter brain energy metabolism, neurotransmission, and cause neurodegenerative disorders. Genetic studies focusing on common nuclear genome vari...

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Bibliographic Details
Main Authors: Adolfo Sequeira, Brandi Rollins, Christophe Magnan, Mannis van Oven, Pierre Baldi, Richard M Myers, Jack D Barchas, Alan F Schatzberg, Stanley J Watson, Huda Akil, William E Bunney, Marquis P Vawter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4444211?pdf=render