Classification of Cells in CTC-Enriched Samples by Advanced Image Analysis

In the CellSearch® system, blood is immunomagnetically enriched for epithelial cell adhesion molecule (EpCAM) expression and cells are stained with the nucleic acid dye 4′6-diamidino-2-phenylindole (DAPI), Cytokeratin-PE (CK), and CD45-APC. Only DAPI+/CK+ objects are presented to t...

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Bibliographic Details
Main Authors: Sanne de Wit, Leonie L. Zeune, T. Jeroen N. Hiltermann, Harry J. M. Groen, Guus van Dalum, Leon W. M. M. Terstappen
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/10/10/377