Crystal structure of intraflagellar transport protein 80 reveals a homo-dimer required for ciliogenesis

Crystal structure of intraflagellar transport protein 80 reveals a homo-dimer required for ciliogenesis

Oligomeric assemblies of intraflagellar transport (IFT) particles build cilia through sequential recruitment and transport of ciliary cargo proteins within cilia. Here we present the 1.8 Å resolution crystal structure of the Chlamydomonas IFT-B protein IFT80, which reveals the architecture of two N-...

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Bibliographic Details
Main Authors: Michael Taschner, Anna Lorentzen, André Mourão, Toby Collins, Grace M Freke, Dale Moulding, Jerome Basquin, Dagan Jenkins, Esben Lorentzen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-04-01
Series:eLife
Subjects:
Chlamydomonas reinhardtii
Cilium
Intraflagelllar transport
protein structure
ciliopathies
IFT80
Online Access:https://elifesciences.org/articles/33067

Internet

https://elifesciences.org/articles/33067

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