Histone Deacetylase 6 and the Disease Mechanisms of α-Synucleinopathies

The abnormal accumulation of α-Synuclein (α-Syn) is a prominent pathological feature in a group of diseases called α-Synucleinopathies, such as Parkinson’s disease, dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). The formation of Lewy bodies (LBs) and glial cytoplasmic inclusions...

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Bibliographic Details
Main Authors: Miguel Lemos, Nadia Stefanova
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnsyn.2020.586453/full