Case Report: Exceptional Response to Avelumab After Failure of Electrochemotherapy in a Patient With Rapidly Progressive, PD-L1-Negative Merkel Cell Carcinoma

Case Report: Exceptional Response to Avelumab After Failure of Electrochemotherapy in a Patient With Rapidly Progressive, PD-L1-Negative Merkel Cell Carcinoma

This case report shows, for the first time, a patient experiencing a complete response after one dose of avelumab following extensive disease progression with prior electrochemotherapy (ECT) treatment. We suggest that ECT may help to establish a tumor microenvironment favorable to immunotherapy. Mer...

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Bibliographic Details
Main Authors: Martina Torchio, Laura Cattaneo, Massimo Milione, Natalie Prinzi, Francesca Corti, Marco Ungari, Andrea Anichini, Roberta Mortarini, Antonio Occhini, Giulia Bertino, Andrea Maurichi, Jorgelina Coppa, Maria Di Bartolomeo, Filippo Guglielmo de Braud, Sara Pusceddu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
skin neoplasms
immunotherapy
electrochemotherapy
MCC
avelumab
Merkel cell carcinoma
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.628324/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.628324/full

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