Programmed death‐ligand 1 gene expression is a prognostic marker in early breast cancer and provides additional prognostic value to 21‐gene and 70‐gene signatures in estrogen receptor‐positive disease

Programmed death‐ligand 1 gene expression is a prognostic marker in early breast cancer and provides additional prognostic value to 21‐gene and 70‐gene signatures in estrogen receptor‐positive disease

Gene and protein expression of programmed death‐ligand 1 (PD‐L1) are prognostic in early breast cancer (BC), but their prognostic information is inconsistent at least in some biological subgroups. The validated prognostic gene signatures (GS) in BC are mainly based on proliferation and estrogen rece...

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Bibliographic Details
Main Authors: Ioannis Zerdes, Emmanouil G. Sifakis, Alexios Matikas, Sebastian Chrétien, Nicholas P. Tobin, Johan Hartman, George Z. Rassidakis, Jonas Bergh, Theodoros Foukakis
Format: Article
Language:English
Published: Wiley 2020-05-01
Series:Molecular Oncology
Subjects:
breast cancer
gene expression
gene signatures
PD‐L1
prognosis
Online Access:https://doi.org/10.1002/1878-0261.12654

Internet

https://doi.org/10.1002/1878-0261.12654

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