Single Chromosome Aneuploidy Induces Genome-Wide Perturbation of Nuclear Organization and Gene Expression

Single Chromosome Aneuploidy Induces Genome-Wide Perturbation of Nuclear Organization and Gene Expression

Chromosomal aneuploidy is a defining feature of carcinomas and results in tumor-entity specific genomic imbalances. For instance, most sporadic colorectal carcinomas carry extra copies of chromosome 7, an aneuploidy that emerges already in premalignant adenomas, and is maintained throughout tumor pr...

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Bibliographic Details
Main Authors: Rüdiger Braun, Scott Ronquist, Darawalee Wangsa, Haiming Chen, Lena Anthuber, Timo Gemoll, Danny Wangsa, Vishal Koparde, Cynthia Hunn, Jens K. Habermann, Kerstin Heselmeyer-Haddad, Indika Rajapakse, Thomas Ried
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558619300119

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http://www.sciencedirect.com/science/article/pii/S1476558619300119

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