Single Chromosome Aneuploidy Induces Genome-Wide Perturbation of Nuclear Organization and Gene Expression

Single Chromosome Aneuploidy Induces Genome-Wide Perturbation of Nuclear Organization and Gene Expression

Chromosomal aneuploidy is a defining feature of carcinomas and results in tumor-entity specific genomic imbalances. For instance, most sporadic colorectal carcinomas carry extra copies of chromosome 7, an aneuploidy that emerges already in premalignant adenomas, and is maintained throughout tumor pr...

Full description

Bibliographic Details
Main Authors: Rüdiger Braun, Scott Ronquist, Darawalee Wangsa, Haiming Chen, Lena Anthuber, Timo Gemoll, Danny Wangsa, Vishal Koparde, Cynthia Hunn, Jens K. Habermann, Kerstin Heselmeyer-Haddad, Indika Rajapakse, Thomas Ried
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558619300119

Similar Items

Similar Items