A New Pentafluorothio-Substituted Curcuminoid with Superior Antitumor Activity

A New Pentafluorothio-Substituted Curcuminoid with Superior Antitumor Activity

A new and readily available pentafluorothiophenyl-substituted N-methyl-piperidone curcuminoid <b>1a</b> was prepared and investigated for its anti-proliferative, pro-apoptotic and cancer stem cell-differentiating activities against a panel of human tumor cell lines derived from various t...

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Bibliographic Details
Main Authors: Benedikt Linder, Leonhard H. F. Köhler, Lisa Reisbeck, Dominic Menger, Dharmalingam Subramaniam, Christel Herold-Mende, Shrikant Anant, Rainer Schobert, Bernhard Biersack, Donat Kögel
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biomolecules
Subjects:
curcumin
piperidone
pentafluorothio group
fluorine
anticancer agents
cell death
Online Access:https://www.mdpi.com/2218-273X/11/7/947

Internet

https://www.mdpi.com/2218-273X/11/7/947

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