An ABCA1-independent pathway for recycling a poorly lipidated 8.1 nm apolipoprotein E particle from glia

An ABCA1-independent pathway for recycling a poorly lipidated 8.1 nm apolipoprotein E particle from glia

Lipid transport in the brain is coordinated by glial-derived lipoproteins that contain apolipoprotein E (apoE) as their primary protein. Here we show that apoE is secreted from wild-type (WT) primary murine mixed glia as nascent lipoprotein subspecies ranging from 7.5 to 17 nm in diameter. Negative-...

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Bibliographic Details
Main Authors: Jianjia Fan, Sophie Stukas, Charmaine Wong, Jennifer Chan, Sharon May, Nicole DeValle, Veronica Hirsch-Reinshagen, Anna Wilkinson, Michael N. Oda, Cheryl L. Wellington
Format: Article
Language:English
Published: Elsevier 2011-09-01
Series:Journal of Lipid Research
Subjects:
apoE
lipoprotein
recycling
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520408521

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520408521

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