Dark matter: are mice the solution to missing heritability?

Genome-wide association studies (GWAS) in humans have identified hundreds of single nucleotide polymorphisms associated with complex traits, yet for most traits studied, the sum total of all these identified variants fail to explain a significant portion of the heritable variation. Reasons for this...

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Bibliographic Details
Main Authors: Clarissa Carlin Parker, Abraham Amos Palmer
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-06-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2011.00032/full