Autonomous targeting of infectious superspreaders using engineered transmissible therapies.

Infectious disease treatments, both pharmaceutical and vaccine, face three universal challenges: the difficulty of targeting treatments to high-risk 'superspreader' populations who drive the great majority of disease spread, behavioral barriers in the host population (such as poor complian...

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Bibliographic Details
Main Authors: Vincent T Metzger, James O Lloyd-Smith, Leor S Weinberger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3060167?pdf=render