Human Epididymis Protein 4 Promotes Events Associated with Metastatic Ovarian Cancer via Regulation of the Extracelluar Matrix

Human Epididymis Protein 4 Promotes Events Associated with Metastatic Ovarian Cancer via Regulation of the Extracelluar Matrix

Human epididymis protein 4 (HE4) has received much attention recently due to its diagnostic and prognostic abilities for epithelial ovarian cancer. Since its inclusion in the Risk of Ovarian Malignancy Algorithm (ROMA), studies have focused on its functional effects in ovarian cancer. Here, we aimed...

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Bibliographic Details
Main Authors: Jennifer R. Ribeiro, Hilary M. Gaudet, Mehreen Khan, Christoph Schorl, Nicole E. James, Matthew T. Oliver, Paul A. DiSilvestro, Richard G. Moore, Naohiro Yano
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Oncology
Subjects:
human epididymis protein 4
epithelial ovarian cancer
metastasis
invasion
haptotaxis
adhesion
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00332/full

Internet

http://journal.frontiersin.org/article/10.3389/fonc.2017.00332/full

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