Two-Photon Laser Scanning Microscopy of the Transverse-Axial Tubule System in Ventricular Cardiomyocytes from Failing and Non-Failing Human Hearts

Objective. The transverse-axial tubule system (TATS) of cardiomyocytes allows a spatially coordinated conversion of electrical excitation into an intracellular Ca2+ signal and consequently contraction. Previous reports have indicated alterations of structure and/or volume of the TATS in cardiac hype...

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Bibliographic Details
Main Authors: Andreas Ohler, Jutta Weisser-Thomas, Valentino Piacentino, Steven R. Houser, Gordon F. Tomaselli, Brian O'Rourke
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Cardiology Research and Practice
Online Access:http://dx.doi.org/10.4061/2009/802373