Binding of Organometallic Ruthenium Anticancer Complexes to DNA: Thermodynamic Base and Sequence Selectivity

Binding of Organometallic Ruthenium Anticancer Complexes to DNA: Thermodynamic Base and Sequence Selectivity

Organometallic ruthenium(II) complexes [(η6-arene)Ru(en)Cl][PF6] (arene = benzene (1), p-cymene (2), indane (3), and biphenyl (4); en = ethylenediamine) are promising anticancer drug candidates both in vitro and in vivo. In this paper, the interactions between ruthenium(II) complexes and 15-...

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Bibliographic Details
Main Authors: Suyan Liu, Aihua Liang, Kui Wu, Wenjuan Zeng, Qun Luo, Fuyi Wang
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:International Journal of Molecular Sciences
Subjects:
organometallic ruthenium complexes
anticancer
oligodeoxynucleotide
base/sequence selectivity
thermodynamics
LC-MS
Online Access:http://www.mdpi.com/1422-0067/19/7/2137

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http://www.mdpi.com/1422-0067/19/7/2137

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