Mesencephalic Astrocyte-Derived Neurotrophic Factor Regulates Morphology of Pigment-Dispersing Factor-Positive Clock Neurons and Circadian Neuronal Plasticity in Drosophila melanogaster

Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) is one of a few neurotrophic factors described in Drosophila melanogaster (DmMANF) but its function is still poorly characterized. In the present study we found that DmMANF is expressed in different clusters of clock neurons. In particular,...

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Main Authors: Wojciech Krzeptowski, Lucyna Walkowicz, Ewelina Krzeptowska, Edyta Motta, Kacper Witek, Joanna Szramel, Terence Al Abaquita, Zbigniew Baster, Zenon Rajfur, Ezio Rosato, Vassilis Stratoulias, Tapio I. Heino, Elżbieta M. Pyza
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Physiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.705183/full