Enantioselective HPLC Analysis to Assist the Chemical Exploration of Chiral Imidazolines

Enantioselective HPLC Analysis to Assist the Chemical Exploration of Chiral Imidazolines

In the present work, we illustrate the ability of high-performance liquid chromatography (HPLC) analysis to assist the synthesis of chiral imidazolines within our medicinal chemistry programs. In particular, a Chiralpak<sup>®</sup> IB<sup>®</sup> column cont...

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Bibliographic Details
Main Authors:	Bruno Cerra, Antonio Macchiarulo, Andrea Carotti, Emidio Camaioni, Ina Varfaj, Roccaldo Sardella, Antimo Gioiello
Format:	Article
Language:	English
Published:	MDPI AG 2020-02-01
Series:	Molecules
Subjects:	cellulose-based chiral stationary phase chiral imidazolines enantiorecognition mechanism hit-to-lead chemical exploration reversed-phase conditions
Online Access:	https://www.mdpi.com/1420-3049/25/3/640

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