A Novel Biosensor to Detect MicroRNAs Rapidly

δ-free F0F1-ATPase within chromatophore was constructed as a novel biosensor to detect miRNA targets. Specific miRNA probes were linked to each rotary β subunits of F0F1-ATPase. Detection of miRNAs was based on the proton flux change induced by light-driven rotation of δ-free F0F1-ATPase. The hybrid...

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Bibliographic Details
Main Authors: Jie-Ying Liao, James Q. Yin, Jia-Chang Yue
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Journal of Sensors
Online Access:http://dx.doi.org/10.1155/2009/671896