Dupuytren’s interventions surgery versus collagenase (DISC) trial: study protocol for a pragmatic, two-arm parallel-group, non-inferiority randomised controlled trial

Dupuytren’s interventions surgery versus collagenase (DISC) trial: study protocol for a pragmatic, two-arm parallel-group, non-inferiority randomised controlled trial

Abstract Background Dupuytren’s contracture is a fibro-proliferative disease of the hands affecting over 2 million UK adults, particularly the white, male population. Surgery is the traditional treatment; however, recent studies have indicated that an alternative to surgery—collagenase clostridium h...

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Bibliographic Details
Main Authors: Joseph Dias, Catherine Arundel, Puvan Tharmanathan, Ada Keding, Charlie Welch, Belen Corbacho, Maria Armaou, Paul Leighton, Christopher Bainbridge, Michael Craigen, Lydia Flett, Samantha Gascoyne, Catherine Hewitt, Elaine James, Sophie James, Nick Johnson, Judy Jones, Catherine Knowlson, Priya Radia, David Torgerson, David Warwick, Michelle Watson
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Trials
Subjects:
Dupuytren’s contracture
Collagenase clostridium histolyticum
Limited fasciectomy
Surgery
Correction
Randomised controlled trial
Online Access:https://doi.org/10.1186/s13063-021-05595-w

Internet

https://doi.org/10.1186/s13063-021-05595-w

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