GLUT1 overexpression enhances glucose metabolism and promotes neonatal heart regeneration

GLUT1 overexpression enhances glucose metabolism and promotes neonatal heart regeneration

Abstract The mammalian heart switches its main metabolic substrate from glucose to fatty acids shortly after birth. This metabolic switch coincides with the loss of regenerative capacity in the heart. However, it is unknown whether glucose metabolism regulates heart regeneration. Here, we report tha...

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Bibliographic Details
Main Authors: Viviana M. Fajardo, Iris Feng, Bao Ying Chen, Cesar A. Perez-Ramirez, Baochen Shi, Peter Clark, Rong Tian, Ching-Ling Lien, Matteo Pellegrini, Heather Christofk, Haruko Nakano, Atsushi Nakano
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88159-x

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https://doi.org/10.1038/s41598-021-88159-x

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