The role of frontostriatal impairment in freezing of gait in Parkinson’s disease

Freezing of gait (FOG) is a disabling symptom of advanced Parkinson’s disease (PD) that leads to an increased risk of falls and nursing home placement. Interestingly, multiple lines of evidence suggest that the manifestation of FOG is related to specific deficits in cognition, such as set shifting a...

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Bibliographic Details
Main Authors: James eShine, Ahmed A Moustafa, Elie eMatar, Michael J Frank, Simon JG Lewis
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Systems Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsys.2013.00061/full