Bone Marrow Soluble Mediator Signatures of Patients With Philadelphia Chromosome-Negative Myeloproliferative Neoplasms

Bone Marrow Soluble Mediator Signatures of Patients With Philadelphia Chromosome-Negative Myeloproliferative Neoplasms

BackgroundEssential thrombocythemia (ET), polycythemia vera (PV), and primary myelofibrosis (PMF) are clonal hematological diseases classified as Philadelphia chromosome-negative myeloproliferative neoplasms (MPN). MPN pathogenesis is associated with the presence of somatic driver mutations, bone ma...

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Main Authors: Juçara Gastaldi Cominal, Maira da Costa Cacemiro, Maria Gabriela Berzoti-Coelho, Illy Enne Gomes Pereira, Fabiani Gai Frantz, Elizabeth Xisto Souto, Dimas Tadeu Covas, Lorena Lobo de Figueiredo-Pontes, Maria Carolina Oliveira, Kelen Cristina Ribeiro Malmegrim, Fabíola Attié de Castro
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
myeloproliferative neoplasms
soluble mediators
inflammation
angiogenesis
cytokines
bone marrow niche
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.665037/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.665037/full

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