Multiple Intravenous Transplantations of Mesenchymal Stem Cells Effectively Restore Long-Term Blood Glucose Homeostasis by Hepatic Engraftment and β-Cell Differentiation in Streptozocin-Induced Diabetic Mice

Multiple Intravenous Transplantations of Mesenchymal Stem Cells Effectively Restore Long-Term Blood Glucose Homeostasis by Hepatic Engraftment and β-Cell Differentiation in Streptozocin-Induced Diabetic Mice

Depletion of pancreatic β-cells results in insulin insufficiency and diabetes mellitus (DM). Single transplantation of mesenchymal stem cells exhibits short-term effects in some preclinical studies. Here, we further investigated the long-term therapeutic effects of multiple intravenous MSC transplan...

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Bibliographic Details
Main Authors: Jennifer H. Ho, Tzu-Ching Tseng, Wei-Hsien Ma, Wei-Kee Ong, Yu-Fan Chen, Ming-Hsiang Chen, Ming-Wei Lin, Chuang-Ye Hong, Oscar K. Lee MD, Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2012-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368911X603611

Internet

https://doi.org/10.3727/096368911X603611

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