Targeted Editing of Myostatin Gene in Sheep by Transcription Activator-like Effector Nucleases

Targeted Editing of Myostatin Gene in Sheep by Transcription Activator-like Effector Nucleases

Myostatin (MSTN) is a secreted growth factor expressed in skeletal muscle and adipose tissue that negatively regulates skeletal muscle mass. Gene knockout of MSTN can result in increasing muscle mass in sheep. The objectives were to investigate whether myostatin gene can be edited in sheep by transc...

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Bibliographic Details
Main Authors: Xinxia Zhao, Wei Ni, Chuangfu Chen, Wujiafu Sai, Jun Qiao, Jingliang Sheng, Hui Zhang, Guozhong Li, Dawei Wang, Shengwei Hu
Format: Article
Language:English
Published: Asian-Australasian Association of Animal Production Societies 2016-03-01
Series:Asian-Australasian Journal of Animal Sciences
Subjects:
Transcription Activator-like Effector Nucleases
Myostatin
Targeted Gene Editing
Sheep Primary Fibroblasts
Online Access:http://www.ajas.info/upload/pdf/ajas-29-3-413.pdf

Internet

http://www.ajas.info/upload/pdf/ajas-29-3-413.pdf

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