A Cellularized Biphasic Implant Based on a Bioactive Silk Fibroin Promotes Integration and Tissue Organization during Osteochondral Defect Repair in a Porcine Model

A Cellularized Biphasic Implant Based on a Bioactive Silk Fibroin Promotes Integration and Tissue Organization during Osteochondral Defect Repair in a Porcine Model

In cartilage tissue engineering, biphasic scaffolds (BSs) have been designed not only to influence the recapitulation of the osteochondral architecture but also to take advantage of the healing ability of bone, promoting the implant’s integration with the surrounding tissue and then bone r...

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Bibliographic Details
Main Authors: Vanessa Pérez-Silos, Nidia K. Moncada-Saucedo, Víctor Peña-Martínez, Jorge Lara-Arias, Iván A. Marino-Martínez, Alberto Camacho, Víktor J. Romero-Díaz, María Lara Banda, Alejandro García-Ruiz, Adolfo Soto-Dominguez, Humberto Rodriguez-Rocha, Norberto López-Serna, Rocky S. Tuan, Hang Lin, Lizeth Fuentes-Mera
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
biphasic scaffold
extracellular cartilage matrix
silk fibroin
osteochondral tissue engineering
Online Access:https://www.mdpi.com/1422-0067/20/20/5145

Internet

https://www.mdpi.com/1422-0067/20/20/5145

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