The Impact of NOTCH Pathway Alteration on Tumor Microenvironment and Clinical Survival of Immune Checkpoint Inhibitors in NSCLC

The Impact of NOTCH Pathway Alteration on Tumor Microenvironment and Clinical Survival of Immune Checkpoint Inhibitors in NSCLC

The treatment of non-small cell lung cancer (NSCLC) with immune checkpoint inhibitors (ICIs) has been proven to induce lasting tumor remission. Screening suitable populations for immunotherapy through predictive markers is an important approach to improving the clinical benefits of patients. Evidenc...

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Bibliographic Details
Main Authors: Xiaohua Li, Yuntao Wang, Xuebing Li, Gang Feng, Sheng Hu, Yifeng Bai
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
NOTCH signaling
non-small cell lung cancer
immune checkpoint inhibitors
tumor microenvironment
immunogenicity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.638763/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.638763/full

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