Down-regulation of SLC25A20 promotes hepatocellular carcinoma growth and metastasis through suppression of fatty-acid oxidation

Abstract Solute carrier family 25 member 20 (SLC25A20) is a mitochondrial-membrane–carrier protein involved in the transport of acylcarnitines into mitochondrial matrix for oxidation. A previous-integrated-proteogenomic study had identified SLC25A20 as one of the top-three prognostic biomarkers in H...

Full description

Bibliographic Details
Main Authors: Peng Yuan, Jiao Mu, Zijun Wang, Shuaijun Ma, Xiuwei Da, Jian Song, Hongxin Zhang, Le Yang, Jibin Li, Jingyue Yang
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03648-1