Comparison of Antigenic Regions Identified on IgG1Fc Using Bioinformatics vs Pepscan Analysis
Epitope mapping allowed the location of antigenic determinants on a protein macromolecule to be identified. In particular, pepscan techniques that utilize a series of overlapping peptides, help detect key amino acid residues that are important in antibody recognition and binding. In a previous study...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2008-01-01
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| Series: | Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders |
| Online Access: | https://doi.org/10.4137/CMAMD.S514 |