Clonal lineage of high grade serous ovarian cancer in a patient with neurofibromatosis type 1

Clonal lineage of high grade serous ovarian cancer in a patient with neurofibromatosis type 1

Neurofibromatosis type 1 (NF1) is caused by mutations in the NF1 gene encoding neurofibromin, which negatively regulates Ras signaling. NF1 patients have an increased risk of developing early onset breast cancer, however, the association between NF1 and high grade serous ovarian cancer (HGSOC) is un...

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Bibliographic Details
Main Authors: Eric J. Norris, Wendell D. Jones, Marius D. Surleac, Andrei J. Petrescu, Darla Destephanis, Qing Zhang, Issam Hamadeh, Jeffrey S. Kneisl, Chad A. Livasy, Ram N. Ganapathi, David L. Tait, Mahrukh K. Ganapathi
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Gynecologic Oncology Reports
Subjects:
Cancer
Ovarian
Neurofibromatosis
NF1
Online Access:http://www.sciencedirect.com/science/article/pii/S2352578918300055

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http://www.sciencedirect.com/science/article/pii/S2352578918300055

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