Regulation of Oligodendrocyte Progenitor Cell Maturation by PPAR: Effects on Bone Morphogenetic Proteins

In EAE (experimental autoimmune encephalomyelitis), agonists of PPARs (peroxisome proliferator-activated receptors) provide clinical benefit and reduce damage. In contrast with PPAR γ , agonists of PPAR δ are more effective when given at later stages of EAE and increase myelin gene expression, sugge...

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Bibliographic Details
Main Authors: Maria Vittoria Simonini, Paul E Polak, Anne I Boullerne, Jeffrey M Peters, Jill C Richardson, Douglas L Feinstein
Format: Article
Language:English
Published: SAGE Publishing 2009-12-01
Series:ASN Neuro
Online Access:https://doi.org/10.1042/AN20090033