Kahweol Ameliorates the Liver Inflammation through the Inhibition of NF-κB and STAT3 Activation in Primary Kupffer Cells and Primary Hepatocytes

Kahweol Ameliorates the Liver Inflammation through the Inhibition of NF-κB and STAT3 Activation in Primary Kupffer Cells and Primary Hepatocytes

Gut derived bacterial endotoxins, such as lipopolysaccharide (LPS), are involved in one of the important mechanisms that lead to inflammation associated with various liver diseases, including nonalcoholic fatty liver disease and alcoholic liver disease. Kahweol is a coffee-specific diterpene present...

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Bibliographic Details
Main Authors: Hye-Young Seo, Mi-Kyung Kim, So-Hee Lee, Jae Seok Hwang, Keun-Gyu Park, Byoung Kuk Jang
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Nutrients
Subjects:
liver inflammation
lipopolysaccharide
kahweol
primary hepatocyte
primary Kupffer cells
Online Access:http://www.mdpi.com/2072-6643/10/7/863

Internet

http://www.mdpi.com/2072-6643/10/7/863

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