Optical coherence tomography and multiphoton microscopy offer new options for the quantification of fibrotic aortic valve disease in ApoE−/− mice

Abstract Aortic valve sclerosis is characterized as the thickening of the aortic valve without obstruction of the left ventricular outflow. It has a prevalence of 30% in people over 65 years old. Aortic valve sclerosis represents a cardiovascular risk marker because it may progress to moderate or se...

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Bibliographic Details
Main Authors: Anett Jannasch, Christian Schnabel, Roberta Galli, Saskia Faak, Petra Büttner, Claudia Dittfeld, Sems Malte Tugtekin, Edmund Koch, Klaus Matschke
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85142-4