Optical coherence tomography and multiphoton microscopy offer new options for the quantification of fibrotic aortic valve disease in ApoE−/− mice
Abstract Aortic valve sclerosis is characterized as the thickening of the aortic valve without obstruction of the left ventricular outflow. It has a prevalence of 30% in people over 65 years old. Aortic valve sclerosis represents a cardiovascular risk marker because it may progress to moderate or se...
Main Authors: | Anett Jannasch, Christian Schnabel, Roberta Galli, Saskia Faak, Petra Büttner, Claudia Dittfeld, Sems Malte Tugtekin, Edmund Koch, Klaus Matschke |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-03-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-85142-4 |
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