Improved Efficacy of Oral Immunotherapy Using Non-Digestible Oligosaccharides in a Murine Cow’s Milk Allergy Model: A Potential Role for Foxp3+ Regulatory T Cells

Improved Efficacy of Oral Immunotherapy Using Non-Digestible Oligosaccharides in a Murine Cow’s Milk Allergy Model: A Potential Role for Foxp3+ Regulatory T Cells

BackgroundOral immunotherapy (OIT) is a promising therapeutic approach to treat food allergic patients. However, there are some concerns regarding its safety and long-term efficacy. The use of non-digestible oligosaccharides might improve OIT efficacy since they are known to directly modulate intest...

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Bibliographic Details
Main Authors: Marlotte M. Vonk, Mara A. P. Diks, Laura Wagenaar, Joost J. Smit, Raymond H. H. Pieters, Johan Garssen, Betty C. A. M. van Esch, Léon M. J. Knippels
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Immunology
Subjects:
cow’s milk allergy
oral immunotherapy
desensitization
non-digestible oligosaccharides
regulatory T cell
butyric acid
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01230/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01230/full

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