Modelling the metabolism of protein secretion through the Tat route in Streptomyces lividans

Modelling the metabolism of protein secretion through the Tat route in Streptomyces lividans

Abstract Background Streptomyces lividans has demonstrated its value as an efficient host for protein production due to its ability to secrete functional proteins directly to the media. Secretory proteins that use the major Sec route need to be properly folded outside the cell, whereas secretory pro...

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Bibliographic Details
Main Authors: José R. Valverde, Sonia Gullón, Rafael P. Mellado
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Microbiology
Subjects:
Biotechnology
Metabolic engineering
Genome-scale metabolic network
FBA modelling
Streptomyces lividans
Tat-dependent protein secretion
Online Access:http://link.springer.com/article/10.1186/s12866-018-1199-3

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http://link.springer.com/article/10.1186/s12866-018-1199-3

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