Neurofibromatosis: Molecular Pathogenesis and Natural Compounds as Potential Treatments

Neurofibromatosis: Molecular Pathogenesis and Natural Compounds as Potential Treatments

The neurofibromatosis syndromes, including NF1, NF2, and schwannomatosis, are tumor suppressor syndromes characterized by multiple nervous system tumors, particularly Schwann cell neoplasms. NF-related tumors are mainly treated by surgery, and some of them have been treated by but are refractory to...

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Bibliographic Details
Main Authors: Anusha Amaravathi, Janet L. Oblinger, D. Bradley Welling, A. Douglas Kinghorn, Long-Sheng Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
neurofibromatosis (NF)
signaling pathway
targeted therapy
natural compounds
eIF4A inhibitors
rocaglamide
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.698192/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.698192/full

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