FLT3 and NPM1 gene mutations in patients with acute myeloid leukemias and the impact of FLT3-ITD mutations on the survival of patients with a normal karyotype

FLT3 and NPM1 gene mutations in patients with acute myeloid leukemias and the impact of FLT3-ITD mutations on the survival of patients with a normal karyotype

Aim. To estimate the extent of FLT3 and NPM1 gene mutations and the impact of mutations of FLT3-ITD on the survival of patients with acute myeloid leukemias (AML). Materials and methods. The nucleus-containing cells of bone marrow and blood were studied in 43 patients with AML. Polymerase chain reac...

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Bibliographic Details
Main Authors: Irina Stepanovna Martynkevich, Sergey Vasil'evich Gritsaev, Mikhail Viktorovich Moskalenko, Marina Petrovna Ivanova, Vasilisa Yur'evna Aksenova, Sof'ya Aleksandrovna Tiranova, Kudrat Mugutdinovich Abdulkadyrov, I S Martynkevich, S V Gritsayev, M V Moskalenko, M P Ivanova, V Yu Aksenova, S A Tiranova, K M Abdulkadyrov
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2010-12-01
Series:Терапевтический архив
Subjects:
flt3-itd
flt3-tkd
npm1
acute myeloid leukemia
normal karyotype
survival
Online Access:https://ter-arkhiv.ru/0040-3660/article/view/30741

Internet

https://ter-arkhiv.ru/0040-3660/article/view/30741

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