Altered Expression Ratio of Actin-Binding Gelsolin Isoforms Is a Novel Hallmark of Mitochondrial OXPHOS Dysfunction

Altered Expression Ratio of Actin-Binding Gelsolin Isoforms Is a Novel Hallmark of Mitochondrial OXPHOS Dysfunction

Mitochondrial oxidative phosphorylation (OXPHOS) defects are the primary cause of inborn errors of energy metabolism. Despite considerable progress on their genetic basis, their global pathophysiological consequences remain undefined. Previous studies reported that OXPHOS dysfunction associated with...

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Bibliographic Details
Main Authors: Alberto García-Bartolomé, Ana Peñas, María Illescas, Verónica Bermejo, Sandra López-Calcerrada, Rafael Pérez-Pérez, Lorena Marín-Buera, Cristina Domínguez-González, Joaquín Arenas, Miguel A. Martín, Cristina Ugalde
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
mitochondria
OXPHOS dysfunction
oxidative stress
actin cytoskeleton
gelsolin isoforms
GSN
Online Access:https://www.mdpi.com/2073-4409/9/9/1922

Internet

https://www.mdpi.com/2073-4409/9/9/1922

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