The biochemistry of acetaminophen hepatotoxicity and rescue: a mathematical model

<p>Abstract</p> <p>Background</p> <p>Acetaminophen (N-acetyl-para-aminophenol) is the most widely used over-the-counter or prescription painkiller in the world. Acetaminophen is metabolized in the liver where a toxic byproduct is produced that can be removed by conjugat...

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Bibliographic Details
Main Authors: Ben-Shachar Rotem, Chen Yifei, Luo Shishi, Hartman Catherine, Reed Michael, Nijhout H Frederik
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Theoretical Biology and Medical Modelling
Subjects:
Online Access:http://www.tbiomed.com/content/9/1/55