Molecular and functional profiling of apical versus basolateral small extracellular vesicles derived from primary human proximal tubular epithelial cells under inflammatory conditions

Molecular and functional profiling of apical versus basolateral small extracellular vesicles derived from primary human proximal tubular epithelial cells under inflammatory conditions

Abstract Proximal tubular epithelial cells (PTEC) are central players in inflammatory kidney diseases. However, the complex signalling mechanism/s via which polarized PTEC mediate disease progression are poorly understood. Small extracellular vesicles (sEV), including exosomes, are recognized as fun...

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Bibliographic Details
Main Authors: Xiangju Wang, Ray Wilkinson, Katrina Kildey, Jacobus P. J. Ungerer, Michelle M. Hill, Alok K. Shah, Ahmed Mohamed, Mriga Dutt, Jeffrey Molendijk, Helen Healy, Andrew J. Kassianos
Format: Article
Language:English
Published: Taylor & Francis Group 2021-02-01
Series:Journal of Extracellular Vesicles
Subjects:
apical
basolateral
human proximal tubular epithelial cells
inflammation
small extracellular vesicles
Online Access:https://doi.org/10.1002/jev2.12064

Internet

https://doi.org/10.1002/jev2.12064

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