Anti-Malignant Ascites Effect of Total Diterpenoids from <i>Euphorbiae Ebracteolatae</i> Radix Is Attributable to Alterations of Aquaporins via Inhibiting PKC Activity in the Kidney

Anti-Malignant Ascites Effect of Total Diterpenoids from <i>Euphorbiae Ebracteolatae</i> Radix Is Attributable to Alterations of Aquaporins via Inhibiting PKC Activity in the Kidney

This study evaluated the anti-ascites effect of total diterpenoids extracted from <i>Euphorbiae Ebracteolatae</i> Radix (TDEE) on malignant ascitic mice and elucidated its underlying mechanism. TDEE was extracted by dichloromethane and subjected to column chromatography. The purity of si...

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Bibliographic Details
Main Authors: Yuanbin Zhang, Dongfang Liu, Fan Xue, Hongli Yu, Hao Wu, Xiaobing Cui, Xingde Zhang, Hepeng Wang
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Molecules
Subjects:
<i>Euphorbia ebracteolata</i> Hayata
diuresis
bioactive components
terpenoids
kidney cells
PKC inhibitor
Online Access:https://www.mdpi.com/1420-3049/26/4/942

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https://www.mdpi.com/1420-3049/26/4/942

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