Succinate Is an Inflammation-Induced Immunoregulatory Metabolite in Macrophages

Succinate Is an Inflammation-Induced Immunoregulatory Metabolite in Macrophages

Immunometabolism revealed the crucial role of cellular metabolism in controlling immune cell phenotype and functions. Macrophages, key immune cells that support progression of numerous inflammatory diseases, have been well described as undergoing vast metabolic rewiring upon activation. The immunome...

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Bibliographic Details
Main Authors: Karl J. Harber, Kyra E. de Goede, Sanne G. S. Verberk, Elisa Meinster, Helga E. de Vries, Michel van Weeghel, Menno P. J. de Winther, Jan Van den Bossche
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Metabolites
Subjects:
succinate
SUCNR1
immunometabolite
macrophage
inflammation
metabolite
Online Access:https://www.mdpi.com/2218-1989/10/9/372

Internet

https://www.mdpi.com/2218-1989/10/9/372

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