Histone Deacetylase Inhibition: An Important Mechanism in the Treatment of Lymphoma

Lymphomas encompass a group of malignancies that originate in the lymph nodes or other lymphoid tissues. Epigenetic modification, especially by histone deacetylase (HDACs), plays a key role during the occurrence and development of lymphomas. Consequently, HDAC inhibitors (HDACIs), a class of gene ex...

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Bibliographic Details
Main Authors: Shan-qi Guo, Yi-zhuo Zhang
Format: Article
Language:English
Published: China Anti-Cancer Association 2012-06-01
Series:Cancer Biology & Medicine
Subjects:
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/14