Transcriptional repression of Hox genes by C. elegans HP1/HPL and H1/HIS-24.

Elucidation of the biological role of linker histone (H1) and heterochromatin protein 1 (HP1) in mammals has been difficult owing to the existence of a least 11 distinct H1 and three HP1 subtypes in mice. Caenorhabditis elegans possesses two HP1 homologues (HPL-1 and HPL-2) and eight H1 variants. Re...

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Bibliographic Details
Main Authors: Maja Studencka, Radosław Wesołowski, Lennart Opitz, Gabriela Salinas-Riester, Jacek R Wisniewski, Monika Jedrusik-Bode
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3441639?pdf=render